Scientific Publications

Control of scar formation, particularly in the skin, is one of the most important clinical objectives of modern medical science. Therefore, Avocet Polymer Technologies is pleased to include this list of scientific publications to assist those who wish to learn more about the treatment of scars.

1. Danielson JR, Walter RJ, Case studies: Use of salicylic acid (Avosil) and hydrogel (Avogel) in limiting scar formation. Journal of Burns and Wounds. 2005 Mar 28; 4(6):119-127. Full article.
   
   
2. Danielson JR, Walter RJ, Salicylic acid may be useful in limiting scar formation. Plast Reconstr Surg. 2004 Oct;114(5):1359-61.
   
   
3. Xiao-Ming, X, Sansores-Garcia, L, Chen, X, Matijevic-Aleksic, N, Du, M, Wu, KK, Suppression of inducible cyclooxygenase 2 gene transcription by aspirin and sodium salicylate. Proc Natl Acad Sci U S A. 1999 Apr 27; 96(9): 5292-5297. Full article.
   
   
4. Wilgus TA, Vodovotz Y, Vittadini E, Clubbs EA, Oberyszyn TM, Reduction of scar formation in full-thickness wounds with topical celecoxib treatment. Wound Repair Regen. 2003 Jan-Feb;11(1):25-34. Abstract available.
   
   
5. Unemori EN, Ehsani N, Wang M, Lee S, McGuire J, Amento EP. Interleukin-1 and transforming growth factor-alpha: synergistic stimulation of metalloproteinases, PGE2, and proliferation in human fibroblasts. Exp Cell Res. 1994 Feb;210(2):166-71. Abstract available.
   
   
6. Kopp E, Ghosh S. Inhibition of NF-kappa B by sodium salicylate and aspirin. Science. 1994 Aug 12;265(5174):956-9. Abstract available.
   
   
7. Grahame R. Transdermal non-steroidal anti-inflammatory agents. Br J Clin Pract. 1995 Jan-Feb;49(1):33-5. Review. Abstract available.
   
   
8. Alpert, D. and Vilcek, J. 2000. "Inhibition of IkB Kinase Activity by Sodium Salicylate in Vitro Does Not Reflect Its Inhibitory Mechanism in Intact Cells". Journal of Biological Chemistry. 275(15):10925-10929.
   
   
9. Suetak, T., Sasai, S., Zhen, Y.X., and Tagami, H. 2000. "Effects of Silicone Gel Sheet on the Stratum Corneum Hydration". British Journal of Plastic Surgery. 53(6):503-507.
10. Schwarb, F.P., Gabard, B., Rufli, T. and Surber, C. 1999. Dermatology. 198(1):44-51.
    
    
11. Degim, I.T., Pugh, W.J. and Hadgraft, J. 1998. "Skin Permeability Data: Anomalous Results". International Journal of Pharmaceutics. 170:129-133.
    
    
12. Lee, R.C., Capelli-Schellpfeffer, M. and Tinsley, E.X. 1998. "Disorders of Excessive Scarring" Chapter 14. Ethnic Considerations in Facial Aesthetic Surgery. 179-191.
    
    
13. Su, C.W., Alizadeh, K., Boddie, A. and Lee, R.C. 1998. "The Problem Scar". Clinics in Plastic Surgery. 25(3):451-465.
    
    
14. Doong, H., Dissanayake, S., Gowrshankar, T.R., et al. 1996. "Calcium Antagonists Alter Cell Shape and Induce Procollagenase Synthesis in Keloid and Normal Human Dermal Fibroblasts". Journal of Burn Care & Rehabilitation. 17(6):497-514.
    
    
15. Phillips, T.J., Gerstein, A.D. and Lordan, V. 1996. "A Randomized Controlled Trial of Hydrocolloid Dressing in the Treatment of Hypertrophic Scars and Keloids". Dermatologic Surgery. 22:775-778.
    
    
16. Ricketts, C.H., Martin, L., Faria, D.T., Saed, G.M., and Fivenson, D.P. 1996. "Cytokine mRNA Changes during the Treatment of Hypertrophic Scars with Silicone and Nonsilicone Gel Dressings". Dermatologic Surgery. 22:955-959
    
    
17. Desmouliere, A., Redard, M., Darby, I., Gabbbiani, G. 1995. "Apoptosis Mediates the Decrease in Cellularity During the Transition Between Granulation Tissue and Scar". American Journal of Pathology. 146:56-66. 11.
    
    
18. Fulton, J.E. 1995. "Silicone Gel Sheeting for the Prevention and Management of Evolving Hypertrophic and Keloid Scars". Dermatologic Surgery. 21:947-951
    
    
19. Reiffel, R.S. 1995. "Prevention of Hypertrophic Scars by Long Term Paper Tape Application". Plastic and Reconstructive Surgery. 96:1715-1718.
    
    
20. Gold, J.H. 1994. "A Controlled Clinical Trial Of Topical Silicone Gel Sheeting in the Treatment of Hypertrophic Scars and Keloids". Journal of the American Academy of Dermatology. 30(3):506-507
    
    
21. Lee, R.C., Doong, H., and Jellema, A. 1994. "The Response of Burn Scars to Intralesional Verapamil". Arch Surg.129:107-111.
    
    
22. Mauviel, A., Halcin, C., Vasiloudes, P., Parks, W.C., Kurkinem, M., and Uitto, J. 1994. "Uncoordinate Regulation of Collagenase, Stromelysin, and Tissue Inhibitor of Metalloproteinases Genes by Prostaglandin-E(2)-Selective Enhancement of Collagenase Gene-Expression in Human Dermal Fibroblasts in Culture". Journal of Cellular Biochemistry. 54(4):465-472.
    
    
23. Gold, J.H. 1993. "Topical Silicone Gel Sheeting in the Treatment of Hypertrophic Scars and Keloids: A Dermatologic Experience". Journal of Dermatologic Surgical Oncology. 19:912-916.
    
    
24. Krieger, L.M., Pan, F., Doong, H. and Lee, R.C. 1993. "Thermal Response of the Epidermis to Surface Gels". Surgical Forum. 738-740.
    
    
25. Sawada, Y., Sone, K. 1992. "Hydration and Occlusion Treatment for Hypertrophic Scars and Keloids". British Journal of Plastic Surgery 45:599-603.
    
    
26. Lee, R.C., and Ping, J. 1990. "Calcium Antagonists Retard Extracellular Matrix Production in Scar Tissue Equivalent". Journal of Surgical Research. 49(5):463-466.
    
    
27. Mercer, N.S.G. 1989. "Silicone Gel in the Treatment of Keloid Scars". British Journal of Plastic Surgery. 42:82-87.
    
    
28. Aggeler, J., Frisch, S.M., Webb, Z. 1984. "Changes In Cell Shape Correlate with Collagenase Gene Expression in Rabbit Synovial Fibroblasts". Journal of Cellular Biology. 98:1662-1671.
    
    
29. Shamberger, R.C., Talbot, T.L., Tipton, H.W., et al. 1981. "The Effect of Ultrasonic and Thermal Treatment on Wounds". Plastic and Reconstructive Surgery. 68:860-870.
    
    
30. Topol, B.M., Lewis, V.L., Beneviste, K. 1981. "The Use of Antihistamine to Retard the Growth of Fibroblasts Derived from Human Skin, Scar, and Keloid". Plastic and Reconstructive Surgery. 68:227-230.